Compensatory response of cardiac lysyl oxidase to chronic volume overload
نویسندگان
چکیده
منابع مشابه
Adaptations of motoneuron properties to chronic compensatory muscle overload.
The aim of the study was to determine whether chronic muscle overload has measurable effect on electrophysiological properties of motoneurons (MNs), and whether duration of this overload influences intensity of adaptations. The compensatory overload was induced in the rat medial gastrocnemius (MG) by bilateral tenotomy of its synergists (lateral gastrocnemius, soleus, and plantaris); as a resul...
متن کاملCardiac hypertrophy is not a required compensatory response to short-term pressure overload.
BACKGROUND Cardiac hypertrophy is considered a necessary compensatory response to sustained elevations of left ventricular (LV) wall stress. METHODS AND RESULTS To test this, we inhibited calcineurin with cyclosporine (CsA) in the setting of surgically induced pressure overload in mice and examined in vivo parameters of ventricular volume and function using echocardiography. Normalized heart ...
متن کاملEffects of dietary phytoestrogens on cardiac remodeling secondary to chronic volume overload in female rats.
Previously, we demonstrated that intact female rats fed a standard rodent diet containing soybean products exhibit essentially no adverse left ventricular (LV) remodeling in response to aortocaval fistula-induced chronic volume overload. We hypothesized that phytoestrogenic compounds in the diet contributed to the female cardioprotection. To test this hypothesis, four groups of female rats were...
متن کاملEffect of Chronic Pressure and Volume Overload
I NCREASE in chamber volume (and therefore increase in wall surface area) is an appropriate adaptation to an increased volume load.' Conversely, a small thick-walled chamber is better suited to deal with a pressure load.2-4 That the human heart so adapts itself to chronic volume and chronic pressure loads is evident from clinical experience and postmortem studies. However, actual measurements o...
متن کاملTemporal changes in integrin-mediated cardiomyocyte adhesion secondary to chronic cardiac volume overload in rats.
Previous studies have established integrins as cell surface receptors that mediate cardiomyocyte-extracellular matrix (ECM) attachments. This study sought to determine the contributions of the myocardial β1- and β3-integrin subunits to ventricular dilatation and coronary flow regulation using a blood-perfused isolated heart preparation. Furthermore, cardiomyocyte adhesion to collagen types I an...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.599.13